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New PDF release: Biochemical Actions of Hormones. Volume 7

By Gerald Litwack (Eds.)

Biochemical activities of Hormones V7

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Resistance to progressive growth of Moloney virus-induced sarcoma in normal mice 4. Mixed lymphocyte reaction (in vivo — in vitro) by lymphoid cells from normal or neonatally thymectomized mice 5. Lymphoid cell response to mitogens (in vivo — in vitro) by cells of normal and athymic, nude mice 6. Resistance to growth of allogeneic and xenogeneic tumors in athymic, nude mice 7. Delay of appearance of abnormal thymocyte differentiation (loss of suppressor function in NZB mice) 8. Antibody production to sheep erythrocytes (in vivo — in vitro) 9.

Burton, and A. White; K. Leung, E. Mihich, P. Burton, and A. White; J. Ehrke, E. Mihich, P. Burton, and A. White. 13. Thymus-Dependent Human Serum Factor (SF) The serum factor of A. Astaldi et al (1976, 1977) acts selectively on hydrocortisone-sensitive thymocytes, stimulates protein synthesis when added in vitro to the cells, and induces human lymphocytes to express an F c receptor for IgM but not for IgG. Of interest is the report (A. Astaldi et al, 1978a) that in normal human thymocytes, the enzyme, terminal deoxyribonucleotidyl transferase, was decreased in activity following incubation of the cells with SF.

Survival in tumor-bearing mice (in conjunction with chemotherapy) Thymosin ai In vitro enhancement of 1. Numbers of E-rosette-forming cells 2. Autologous rosette-forming cells in cancer patients 3. Secondary T-cell-dependent IgG, IgM, and IgA antibody responses 4. Macrophage inhibitory factor 5. Expression of Ly-1,-2,-3 positive cells in human lymphocytes 6. T-cell-dependent specific antibody production 7. Helper T cells 8. Suppression of terminal deoxyribonucleotidyl transferase activity in murine thymocytes 9.

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