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Download e-book for iPad: Biomedical Applications of Peptide-, Glyco- and Glycopeptide by Jaroslav Sebestik, Milan Reinis, Jan Jezek

By Jaroslav Sebestik, Milan Reinis, Jan Jezek

Dendrimers are again and again branched and approximately round huge molecules. they are often utilized in numerous scientific purposes, resembling anticancer polymeric nanomedicines and nanocarriers, gene vendors and vectors in gene supply, distinction brokers for molecular imaging and vaccines opposed to infectious ailments and melanoma. The hugely branched, multivalent nature and molecular structure of dendrimers cause them to excellent instruments for numerous tissue engineering purposes. This e-book describes diversified different types of dendrimers, their biomedical and physico-chemical functions in addition to convergent and divergent syntheses, click on chemistry and ligation innovations. it's a wealthy resource of knowledge for researchers in biochemistry and pharmacology engaged on drug improvement in addition to for natural chemists who're engaged in synthesis of dendrimers.

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Extra resources for Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

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Evolutionary glycomics: characterization of milk oligosaccharides in primates. J. Proteom. Res. 10(4), 1548–1557 (2011) 35. : Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature 480(7376), 254–258 (2011) References 27 36. : Lipomic profiling in drug discovery, development and clinical trial evaluation. Curr. Opin. Drug Discover. Devel. 7(1), 112–117 (2004) 37. : Carbohydrates as the next frontier in pharmaceutical research. Chem. Eur. J. 11(11), 3194–3206 (2005) 38.

Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers. Biomacromolecules 10(5), 1195–1202 (2009) 24. : Water-soluble conjugated polyelectrolyte with pendant glycocluster: synthesis and its interaction with heparin. Polymer 52(2), 383–390 (2011) References 17 25. : Synthesis of dendrigraft poly( -caprolactone)s using side hydroxyl groups for the grafting of branch chains. Macromol. Rapid. Commun. 32(22), 1839–1845 (2011) 26. : Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands.

J. 15(47), 13232–13240 (2009) 24. : Synthesis of dodecavalent fullerene-based glycoclusters and evaluation of their binding properties towards a bacterial lectin. Chem. Eur. J. 17(11), 3252–3261 (2011) 25. : Design and creativity in synthesis of multivalent neoglycoconjugates. Adv. Carbohydr. Chem. Biochem. 63, 165–393 (2010) 26. : Hexaphenylbenzene as a rigid template for the straightforward syntheses of “star-shaped” glycodendrimers. J. Org. Chem. 76(2), 724–727 (2011) 27. : Unexpected in vivo antiinflammatory activity observed for simple, surface functionalized poly(amidoamine) dendrimers.

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