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Get Cases & Concepts Step 1: Pathophysiology Review PDF

By Aaron B. Caughey

Instances & recommendations Step 1: Pathophysiology evaluation is helping scientific scholars arrange for USMLE Step 1 by means of combining simple technology themes with scientific facts. operating via 88 medical circumstances, the reader earnings event studying situations, learns vintage shows of universal ailments and syndromes, and integrates easy technological know-how recommendations with scientific purposes. Sections disguise cardiovascular, pulmonary, renal, gastrointestinal, hematology, oncology, endocrinology, rheumatology, replica, and neuroscience. instances are via USMLE-style questions with solutions and rationales. Thumbnail and Key thought bins spotlight key proof. A spouse web site bargains totally searchable textual content on-line.

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VT can also be subclassified by morphology as monomorphic versus polymorphic. All the QRS complexes are the same shape in monomorphic VT because the tachycardia evolves from a single arrhythmogenic focus. The most common cause of monomorphic VT is re-entry in scarred myocardium created after MI. In polymorphic VT, the QRS complexes are different shapes because the tachycardia evolves from several ventricular foci. Polymorphic VT is usually associated with active ischemia rather than with re-entry from myocardial scarring.

The mitral valve apparatus includes not only the valve itself but also the chordae tendineae, papillary muscles, and the mitral valve annulus. Malfunction of any of these components can lead to mitral valve regurgitation. The most common cause of MR is myxomatous degeneration mitral valve prolapse followed by ischemic heart disease. Other causes of MR include endocarditis, rheumatic heart disease, collagen vascular disease, chordal rupture, and dexfenfluramine and fenfluramine use. In acute-onset MR, there is an acute increase in LV preload from both the pathologic regurgitant fraction and the physiologic pulmonary venous inflow.

A Holter monitor records several episodes of a regular narrow complex tachycardia at 160 beats/min. Review of the event monitor diary is notable for the association between coffee intake and tachycardia initiation. The patient is instructed to splash cold water on her face during palpitations. When she does so, the palpitations promptly terminate. 8ºC; HR 110 beats/min; BP 90/50 mm Hg; RR 22 breaths/min. H/N: JVP 6 cm, 1-cm nodule in left thyroid lobe. Chest: Clear to exam. Cardiac: Tachycardic with normal impulse, normal S1 and S2 with no murmurs.

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